Trophoblast Cell Surface Antigen 2 gene (TACSTD2) expression in primary breast cancer.
Neelima VidulaChristina YauHope RugoPublished in: Breast cancer research and treatment (2022)
TACSTD2 gene expression was seen in all breast cancer subtypes particularly luminal A and TNBC, and correlated with the expression of genes involved in cell epithelial transformation, adhesion, and proliferation, which contribute to tumor growth. These results support the investigation of TROP2 ADC in all subtypes of breast cancer.
Keyphrases
- gene expression
- poor prognosis
- cell surface
- dna methylation
- binding protein
- single cell
- signaling pathway
- genome wide
- stem cells
- magnetic resonance imaging
- computed tomography
- copy number
- staphylococcus aureus
- cystic fibrosis
- young adults
- transcription factor
- diffusion weighted
- diffusion weighted imaging
- cell migration