Canine invasive mammary carcinomas as models of human breast cancer. Part 2: immunophenotypes and prognostic significance.
Jérôme AbadieFrédérique NguyenDelphine LoussouarnLaura PeñaAdelina GamaNatascha RiederAnton BelousovIngrid BemelmansLaëtitia JaillardonCatherine IbischMario CamponePublished in: Breast cancer research and treatment (2017)
In our cohort, triple-negative CMCs largely predominated (76%), were much more prevalent than in human beings, and showed an aggressive natural behavior after mastectomy. Dogs are thus potent valuable spontaneous models to test new therapeutic strategies for this particular subtype of breast cancer.