Association of preoperative hyponatremia with surgical outcomes: a systematic review and meta-analysis of 32 observational studies.
Chong Boon TeoMing Yi GanRyan Yong Kiat TayWann Jia LohNe Hooi Will LohPublished in: The Journal of clinical endocrinology and metabolism (2022)
Our meta-analysis suggests that preoperative hyponatremia is associated with poorer early mortality and major morbidity outcomes in surgical patients. Hyponatremia is also a specific prognosticator for major complications in surgical patients, reiterating its potential use as a clinical indicator of poor outcomes.