Clinical and Metabolic Signature of UNC13A rs12608932 Variant in Amyotrophic Lateral Sclerosis.

Andrea CalvoAntonio CanosaCristina MogliaUmberto ManeraMaurizio GrassanoRosario VastaFrancesca PalumboPaolo CugnascoSalvatore GalloneMaura BrunettiFabiola De MarchiVincenzo ArenaMarco PaganiCliffton L DalgardSonja W ScholzRuth ChiaLucia CorradoSandra DalfonsoLetizia MazziniBryan J TraynorAdriano Chio

Published in: Neurology. Genetics (2022)

to the ALS genetic panel to refine the individual prognostic prediction and reduce heterogeneity in clinical trials.

Keyphrases

clinical trial
genome wide
single cell
amyotrophic lateral sclerosis
gene expression
phase ii
randomized controlled trial
dna methylation
open label
double blind