Exercise modulation of tumour perfusion and hypoxia to improve radiotherapy response in prostate cancer.
Oliver SchumacherDaniel A GalvãoDennis R TaaffeRaphael CheeNigel SpryRobert U NewtonPublished in: Prostate cancer and prostatic diseases (2020)
Exercise is a potentially promising adjunct therapy for men with PCa undergoing radiotherapy that may increase its effectiveness. However, exercise-induced tumour radiosensitisation remains to be confirmed in preclinical and clinical trials, as does the optimal exercise prescription to elicit such effects.
Keyphrases
- high intensity
- prostate cancer
- clinical trial
- early stage
- physical activity
- resistance training
- locally advanced
- radiation therapy
- randomized controlled trial
- systematic review
- radical prostatectomy
- endothelial cells
- squamous cell carcinoma
- stem cells
- body composition
- bone marrow
- middle aged
- open label
- magnetic resonance