Correlation of lipid peroxidation and nitric oxide metabolites, trace elements, and antioxidant enzymes in patients with sickle cell disease.
Charles Antwi-BoasiakoGifty Boatemaah DankwahRobert AryeeCharles Hayfron-BenjaminGeorge AboagyeAndrew D CampbellPublished in: Journal of clinical laboratory analysis (2020)
Findings from this study suggest a link between lipid peroxidation and Cu in HbSS patients with VOC. Increased MDA/NOx ratio may contribute to sickle cell pathophysiology by promoting oxidative stress.