Cell-free fat extract improves ovarian function and fertility in mice with premature ovarian insufficiency.

Mengyu LiuDan ZhangXiaowei ZhouJingru DuanYanqin HuWenjie ZhangQiang LiuBufang XuAijun Zhang

Published in: Stem cell research & therapy (2022)

The treatment of CEFFE inhibited the apoptosis of granulosa cells and contributed to the recovery of ovarian function, as well as the fertility of mice with POI.

Keyphrases

cell free
cell cycle arrest
induced apoptosis
oxidative stress
high fat diet induced
endoplasmic reticulum stress
cell death
adipose tissue
pi k akt
type diabetes
childhood cancer
fatty acid
signaling pathway
cell proliferation
smoking cessation