Early weaning leads to specific glucocorticoid signalling in fat depots of adult rats.
Rosiane Aparecida MirandaCarla Bruna PietrobonIala Milene BertassoVanessa S Tavares RodriguesBruna Pereira LopesCamila CalvinoElaine de OliveiraEgberto Gaspar de MouraPatrícia Cristina LisboaPublished in: Endocrine (2019)
The accumulated adiposity induced by EW exhibited distinct mechanisms depending on gender, specific fat deposition and GC metabolism and action. The higher proportion of VAT/SAT in both sets of EW males may be related to the action of GC in these tissues, and the higher conversion of GC in SAT in females may explain the differences in the fat distribution.