A Real-World, Observational Study of the Initiation, Use, and Effectiveness of Basal-Bolus or Premixed Insulin in Japanese People with Type 2 Diabetes.
Hideaki MiyoshiMike BaxterTakeshi KimuraMasakatsu HattoriYukiko MorimotoDion MarinkovichMasami TamiwaTakahisa HirosePublished in: Diabetes therapy : research, treatment and education of diabetes and related disorders (2021)
Greater HbA1c reductions, but a higher incidence of hypoglycaemia, were reported with BB versus premixed regimens, while both cohorts demonstrated clinically meaningful reductions in HbA1c during follow-up. After initiation, most premixed regimens remained unchanged, whereas switches from BB to less intensive regimens were numerous, in accordance with the use of BB for a limited duration to improve FPG and PPG control.