IL-22-expressing CD4+ AhR+ T lymphocytes are associated with RANKL-mediated alveolar bone resorption during experimental periodontitis.
Gustavo MonasterioVictoria BudiniBaltasar FernándezFrancisca CastilloCarolina RojasCarla R AlvarezEmilio Alfredo CafferataEmiliano VicencioBastián I CortésCristian CortezRolando VernalPublished in: Journal of periodontal research (2019)
This study demonstrates the increase of IL-22-expressing CD4+ AhR+ T lymphocytes in periodontitis-affected tissues and shows a positive correlation between IL-22, RANKL expression, and alveolar bone resorption.