Immune evasion in lung metastasis of leiomyosarcoma: upregulation of EPCAM inhibits CD8 + T cell infiltration.

Masaya KanahoriEijiro ShimadaYoshihiro MatsumotoMakoto EndoToshifumi FujiwaraAkira NabeshimaTakeshi HiroseKengo KawaguchiRyunosuke OyamaYoshinao OdaYasuharu Nakashima

Published in: British journal of cancer (2024)

T cell migration. Our findings suggest that EPCAM could serve as a potential novel therapeutic target for leiomyosarcoma.

Keyphrases

cell migration
cell adhesion
circulating tumor cells
poor prognosis
cell proliferation
signaling pathway
human health
risk assessment