Molecularly Imprinted Polymer-Based Sensors for SARS-CoV-2: Where Are We Now?
Aysu YarmanSevinc KurbanogluPublished in: Biomimetics (Basel, Switzerland) (2022)
Since the first reported case of COVID-19 in 2019 in China and the official declaration from the World Health Organization in March 2021 as a pandemic, fast and accurate diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has played a major role worldwide. For this reason, various methods have been developed, comprising reverse transcriptase-polymerase chain reaction (RT-PCR), immunoassays, clustered regularly interspaced short palindromic repeats (CRISPR), reverse transcription loop-mediated isothermal amplification (RT-LAMP), and bio(mimetic)sensors. Among the developed methods, RT-PCR is so far the gold standard. Herein, we give an overview of the MIP-based sensors utilized since the beginning of the pandemic.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- loop mediated isothermal amplification
- molecularly imprinted
- low cost
- coronavirus disease
- sensitive detection
- crispr cas
- solid phase extraction
- genome editing
- high resolution
- transcription factor
- real time pcr
- gene expression
- simultaneous determination
- tandem mass spectrometry
- quantum dots
- liquid chromatography