Biomarkers of erosive arthritis in systemic lupus erythematosus: Application of machine learning models.
Fulvia CeccarelliMarco SciandroneCarlo PerriconeGiulio GalvanEnrica CiprianoAlessandro GalligariTommaso LevatoTania ColasantiLaura MassaroFrancesco NatalucciFrancesca Romana SpinelliCristiano AlessandriGuido ValesiniFabrizio ContiPublished in: PloS one (2018)
The application of Machine Learning Models allowed to identify factors associated with US-detected erosive bone damage in a large SLE cohort and their relevance in determining this phenotype. Although the scope of this study is limited by the small sample size and its cross-sectional nature, the results suggest the relevance of ACPA and anti-CarP antibodies in the development of erosive damage as also pointed out in other studies.