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Face validity of the Kids' ITP Tools (KIT) in the era of thrombopoietin receptor agonists.

Catherine McGuireNancy L YoungJoel LivingstonVinita DhirVictor S BlanchetteMelanie Kirby-AllenRobert J Klaassen
Published in: Pediatric blood & cancer (2024)
The Kids' ITP Tools (KIT) is a questionnaire to assess quality of life of children with immune thrombocytopenia (ITP). The aim of this study was to update this previously validated tool to align with changes in clinical practice, specifically, treatment with thrombopoietin receptor agonists (TPO-RAs). Children aged 1-18 with ITP and/or their families were recruited to participate in interviews to review the KIT. Twenty-six interviews were conducted. Based on interview data from children and families, current guidelines, and expert opinion, five changes were made to the KIT in order to improve its face validity.
Keyphrases
  • clinical practice
  • young adults
  • cross sectional
  • machine learning
  • replacement therapy
  • data analysis
  • wild type