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Associations of changes in reported and estimated protein and energy intake with changes in insulin resistance, glycated hemoglobin, and BMI during the PREVIEW lifestyle intervention study.

Mathjis DrummenTanja C AdamIan A MacdonaldElli JaloThomas M LarssenJ Alfredo MartinezTeodora Handjiev-DarlenskaJennie C Brand-MillerSally D PoppittGareth StrattonKirsi H PietiläinenMoira A TaylorSantiago Navas-CarreteroSvetoslav HandjievRoslyn MuirheadMarta P SilvestreNils SwindellMaija Huttunen-LenzWolfgang SchlichtTony LamJouko SundvallLaura RamanEdith FeskensAngelo TremblayAnne RabenMargriet S Westerterp-Plantenga
Published in: The American journal of clinical nutrition (2021)
During weight-loss maintenance in adults with prediabetes, increase in protein intake and decrease in energy intake were not associated with decrease in HOMA-IR beyond associations with decrease in BMI. Increases in PEst and PRep were associated with decrease in HbA1c.This trial was registered at clinicaltrials.gov as NCT01777893.
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