The development and validation of tau PET tracers: current status and future directions.

Nobuyuki OkamuraRyuichi HaradaAiko IshikiAkio KikuchiTadaho NakamuraYukitsuka Kudo

Published in: Clinical and translational imaging (2018)

Tau PET tracers have enabled in vivo quantification of PHF-tau burden in human brains. Tau PET can help in understanding the underlying cause of dementia symptoms, and in patient selection for clinical trials of anti-dementia therapies.

Keyphrases

cerebrospinal fluid
current status
pet ct
positron emission tomography
computed tomography
clinical trial
mild cognitive impairment
pet imaging
cognitive impairment
endothelial cells
case report
physical activity
sleep quality
induced pluripotent stem cells
pluripotent stem cells
double blind