Apolipoprotein D as a Potential Biomarker and Construction of a Transcriptional Regulatory-Immune Network Associated with Osteoarthritis by Weighted Gene Coexpression Network Analysis.

Yong QinJia LiYonggang ZhouChengliang YinYi LiMing ChenYinqiao DuTiejian LiJinglong Yan

Published in: Cartilage (2021)

Our results suggest that the expression level of apolipoprotein D (APOD) was correlated with OA. Furthermore, transcriptional regulatory-immune network was constructed, which may contribute to OA therapy.

Keyphrases

network analysis
transcription factor
knee osteoarthritis
gene expression
poor prognosis
genome wide identification
wastewater treatment
rheumatoid arthritis
copy number
genome wide
binding protein
long non coding rna
magnetic resonance
oxidative stress
dna methylation
heat shock protein