Pre-implantation kidney biopsy: value of the expertise in determining histological score and comparison with the whole organ on a series of discarded kidneys.
Ilaria GirolamiGiovanni GambaroClaudio GhimentonSerena BeccariAnna CaliòMatteo BrunelliLuca NovelliUgo BoggiDaniela CampaniGianluigi ZazaLuigino BoschieroJosé Ignacio LópezGuido MartignoniAntonia D'ErricoDorry SegevDesley NeilAlbino EccherPublished in: Journal of nephrology (2019)
Our data suggests that the creation of a pool of specialist pathologists would improve organ utilization. Moreover, biopsies are not representative of the whole organ. As the Remuzzi score on biopsy is a major reasons for discard, a quota of transplantable kidneys may be erroneously discarded. Refinement in Remuzzi cut-offs based on expert reporting and recognition of sampling error of biopsies in correlation with clinical outcome data should be undertaken.