Longitudinal diffusion and volumetric kinetics of head and neck cancer magnetic resonance on a 1.5T MR-Linear accelerator hybrid system: A prospective R-IDEAL Stage 2a imaging biomarker characterization/ pre-qualification study.
null nullnull nullDina M ElHabashyKareem A WahidRenjie HeBrigid McDonaldJillian RigertSamuel J MulderTze Yee LimXin WangJinzhong YangYao DingMohamed A NaserSweet Ping NgHouda BahigTravis C SalzilloKathryn E PrestonMoamen AbobakrMohamed A ShehataEnas A ElkhoulyHagar A AlagizyAmira H HegazyMustefa MohammadseidChris TerhaardMarielle PhilippensDavid I RosenthalJihong WangStephen Y LaiAlex DresnerJohn C ChristodouleasAbdallah Sherif Radwan MohamedClifton David FullerPublished in: medRxiv : the preprint server for health sciences (2023)
Assessment of ADC kinetics at regular intervals throughout RT seems to be correlated with RT response. Further studies with larger cohorts and multi-institutional data are needed for validation of ΔADC as a model for prediction of response to RT.