Identification of Monocyte-Associated Genes Related to the Instability of Atherosclerosis Plaque.
Wentao QinFu GanRiguan LiangJing LiXiaomei LaiYongfa DaiJie LiuPublished in: Oxidative medicine and cellular longevity (2022)
Overexpression of CXCL3, GK, FPR1, and LST1 was advanced recognition and intervention factors for unstable plaques, which might become targets for atherosclerosis rupture prevention. We also analyzed the potential mechanisms of CEG from inflammatory and oxidative stress pathways.
Keyphrases
- oxidative stress
- bioinformatics analysis
- cardiovascular disease
- randomized controlled trial
- dendritic cells
- cell proliferation
- dna damage
- coronary artery disease
- genome wide
- endothelial cells
- transcription factor
- ischemia reperfusion injury
- diabetic rats
- induced apoptosis
- genome wide identification
- human health
- gene expression
- type diabetes
- dna methylation
- immune response