Mesenchymal Stem Cells: A New Choice for Nonsurgical Treatment of OA? Results from a Bayesian Network Meta-Analysis.
Ziqin CaoYajia LiFuqiang GaoRen WuPengcheng DouWanchun WangQiangxiang LiPublished in: BioMed research international (2021)
The results show that MSCs relieve pain, stiffness, and dysfunction due to OA better than PRP, HA, and GCs and are not statistically correlated with greater safety concerns. More high-quality trials are needed to reconfirm the findings of this study, however, standardization of preparation of MSCs and PRP should be investigated in the future.
Keyphrases
- mesenchymal stem cells
- umbilical cord
- systematic review
- platelet rich plasma
- chronic pain
- knee osteoarthritis
- bone marrow
- meta analyses
- pain management
- cell therapy
- current status
- oxidative stress
- randomized controlled trial
- neuropathic pain
- stem cells
- molecularly imprinted
- atomic force microscopy
- decision making
- mass spectrometry
- high resolution
- combination therapy
- replacement therapy
- liquid chromatography