Prospective randomized controlled blinded clinical trial evaluating biomarkers of acute kidney injury following 6% hydroxyethyl starch 130/0.4 or Hartmann's solution in dogs.
Corrin J BoydClaire Rebecca SharpMelissa A ClausAnthea L RaisisGiselle HosgoodLisa SmartPublished in: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) (2021)
There were no differences in change over time of urine AKI biomarkers in dogs treated with 10 - 40 mL/kg HES or CRYST over 24 hours. Larger clinical trials with patient-centered outcomes are required to investigate the safety of HES in dogs.