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Nonnutritive Sweeteners in Weight Management and Chronic Disease: A Review.

Allison C SylvetskyKristina I Rother
Published in: Obesity (Silver Spring, Md.) (2018)
NNS consumption is associated with higher body weight and metabolic disease in observational studies. In contrast, randomized controlled trials demonstrate that NNSs may support weight loss, particularly when used alongside behavioral weight loss support. Additional long-term, well-controlled intervention studies in humans are needed to determine the effects of NNSs on weight, adiposity, and chronic disease under free-living conditions.
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