Testosterone treatment and the risk of aggressive prostate cancer in men with low testosterone levels.

Thomas J WalshMolly M ShoresChloe A KrakauerChristopher W ForsbergAlexandra E FoxKathryn P MooreAnna KorpakSusan R HeckbertSteven B ZeliadtChloe E KinseyMary Lou ThompsonNicholas L SmithAlvin M Matsumoto

Published in: PloS one (2018)

Among men with low testosterone levels and normal PSA, testosterone treatment was not associated with an increased risk of aggressive or any CaP. The clinical risks and benefits of testosterone treatment can only be fully addressed by large, longer-term randomized controlled trials.

Keyphrases

prostate cancer
replacement therapy
randomized controlled trial
radical prostatectomy
systematic review
smoking cessation
human health