Prognostic implications of markers of the metabolic phenotype in human cutaneous melanoma.
Laura Nájera-BotelloMiguel Alonso-JuarranzMaría-Concepción Garrido-RuízC BallestínL MoyaM Martínez-DíazR CarrilloÁngeles Juarranz de la FuenteFederico RojoJosé M CuezvaJosé Luis Rodriguez-PeraltoPublished in: The British journal of dermatology (2019)
A profound alteration in the mitochondrial and glycolytic proteins and in the BEC index occurs in the progression of melanoma, which correlates with worse outcome, supporting that the alteration of the metabolic phenotype is crucial in melanoma transformation.