Curcumin Derivatives Verify the Essentiality of ROS Upregulation in Tumor Suppression.

Ikuko NakamaeTsumoru MorimotoHiroki ShimaMasafumi ShionyuHisayo FujikiNoriko Yoneda-KatoTakashi YokoyamaShigehiko KanayaKiyomi KakiuchiTsuyoshi ShiraiEdy MeiyantoJun-Ya Kato

Published in: Molecules (Basel, Switzerland) (2019)

The analysis of novel curcumin derivatives established the importance of ROS upregulation in suppression of tumorigenesis, and these compounds are potentially useful for the development of an anti-cancer drug with few side effects.

Keyphrases

poor prognosis
cell death
dna damage
reactive oxygen species
cell proliferation
signaling pathway
structure activity relationship
long non coding rna
emergency department