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Immunological response of human leucocytes after exposure to lipopolysaccharides from Porphyromonas gingivalis.

Sara AlizadehgharibAnna-Karin ÖstbergAgnes Dahlstrand RudinUlf DahlgrenKarin Christenson
Published in: Clinical and experimental dental research (2020)
LPS from P. gingivalis has the ability to affect both human neutrophils and PBMCs with regard to cytokine production, cell death and production of NETs. LPS from P. gingivalis could be involved in the pathogenesis of periodontitis, and our results may contribute information regarding possible markers for diagnosis and targets for treatment of periodontal disease.
Keyphrases
  • endothelial cells
  • cell death
  • inflammatory response
  • induced pluripotent stem cells
  • pluripotent stem cells
  • anti inflammatory
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  • signaling pathway
  • cell proliferation