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The influence of hippocampal atrophy on the cognitive phenotype of dementia with Lewy bodies.

Greg J ElderKaren MactierSean J CollobyRosie WatsonAndrew M BlamireJohn T O'BrienJohn-Paul Taylor
Published in: International journal of geriatric psychiatry (2017)
In this large sample, these results are in agreement with other studies indicating that hippocampal atrophy is less severe in DLB than AD. Hippocampal atrophy and medial temporal lobe cortical thickness were associated with the severity of cognitive symptoms, suggesting that atrophy in these structures, as a potential proxy of AD pathology, may partly mediate specific DLB cognitive symptoms. © 2017 The Authors. International Journal of Geriatric Psychiatry Published by John Wiley & Sons Ltd.
Keyphrases
  • cerebral ischemia
  • mild cognitive impairment
  • randomized controlled trial
  • optical coherence tomography
  • cognitive impairment
  • blood brain barrier
  • drug induced