Abnormalities in Cardiac Structure and Function among Individuals with CKD: The COMBINE Trial.
Ann Andee WangXuan CaiAnand SrivastavaPottumarthi V PrasadStuart M SpragueJames CarrMyles WolfJoachim H IxGeoffrey A BlockMichel ChoncholKalani L RaphaelAlfred K CheungDominic S RajJennifer J GassmanAmir Ali RahseparJohn P MiddletonLinda F FriedRoberto SarnariTamara IsakovaRupal MehtaPublished in: Kidney360 (2021)
Individuals with CKD stages 3b-4 have evidence of cMRI abnormalities. Albuminuria was independently associated with diastolic dysfunction, as assessed by mitral valve E/A ratio, in individuals with CKD with and without clinical CVD. Albuminuria was not associated with change in any cMRI parameter.