Histone-specific CD4+ T-cell plasticity in active and quiescent systemic lupus erythematosus.

Giuseppe Alvise RamirezElena TassiMaddalena NovielloBenedetta A MazziLuca MoroniLorena CitterioLaura ZagatoEnrico TombettiMatteo DoglioElena M BaldisseraEnrica P BozzoloChiara BoniniLorenzo DagnaAngelo A Manfredi

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2023)

Histone-specific T-cells are selectively detected in patients with SLE and their concentration in the blood varies with disease activity, suggesting that they represent innovative tools for patient stratification and therapy.

Keyphrases

systemic lupus erythematosus
disease activity
rheumatoid arthritis
rheumatoid arthritis patients
ankylosing spondylitis
dna methylation
juvenile idiopathic arthritis
case report
stem cells
mesenchymal stem cells
gene expression