Adolescent use of combined hormonal contraception and peak bone mineral density accrual: A meta-analysis of international prospective controlled studies.
Azita GoshtasebiTatjana Subotic BrajicDelia ScholesTamara Beres Lederer GoldbergAbbey BerensonJerilynn C PriorPublished in: Clinical endocrinology (2019)
Given that adolescent exposure to CHC appears to be increasing, this evidence for potential impairment of peak spinal BMD accrual is of concern and suggests a potential public health problem. Randomized controlled trial data are needed to determine CHC effects on adolescent bone health.
Keyphrases
- bone mineral density
- public health
- mental health
- young adults
- postmenopausal women
- randomized controlled trial
- body composition
- human health
- healthcare
- childhood cancer
- spinal cord
- study protocol
- big data
- electronic health record
- type diabetes
- risk assessment
- polycystic ovary syndrome
- machine learning
- health information
- systematic review
- adipose tissue
- artificial intelligence
- data analysis