Initial report on feasibility of PET/CT-based image-guided moderate hypofractionated thoracic irradiation in node-positive non-small cell lung Cancer patients with poor prognostic factors and strongly diminished lung function: a retrospective analysis.
Chukwuka EzeJulian TaugnerOlarn RoengvoraphojNina-Sophie Schmidt-HegemannLukas KäsmannCherylina WijayaClaus BelkaFarkhad ManapovPublished in: Radiation oncology (London, England) (2019)
Hypo-IGRT can be considered for individual and closely monitored patients with locally advanced node-positive NSCLC with highly compromised pulmonary function. No severe pulmonary toxicity and significant decline of pulmonary function parameters was observed in our cohort. Currently, this protocol is being assessed in an ongoing single-centre prospective study.
Keyphrases
- pet ct
- lung function
- prognostic factors
- locally advanced
- lymph node
- cystic fibrosis
- chronic obstructive pulmonary disease
- radiation therapy
- air pollution
- small cell lung cancer
- positron emission tomography
- squamous cell carcinoma
- rectal cancer
- neoadjuvant chemotherapy
- pulmonary hypertension
- randomized controlled trial
- spinal cord
- brain metastases
- early onset
- high intensity
- computed tomography
- clinical trial
- spinal cord injury
- study protocol