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Persistence and effectiveness of the IL-12/23 pathway inhibitor ustekinumab or tumour necrosis factor inhibitor treatment in patients with psoriatic arthritis: 1-year results from the real-world PsABio Study.

Laure GossecStefan SiebertPaul BergmansKurt de VlamElisa GremeseBeatríz Joven-IbáñezTatiana V KorotaevaFrederic LavieWim NoëlMichael T NurmohamedPetros P SfikakisElke TheanderJosef S Smolen
Published in: Annals of the rheumatic diseases (2022)
In the real-world PsABio Study, after 1 year of treatment, although unadjusted persistence was numerically slightly higher for ustekinumab versus TNFi and unadjusted effectiveness was numerically slightly higher for TNFi versus ustekinumab, the PS-adjusted comparisons demonstrated comparable overall persistence, effectiveness and safety for both modes of action in PsA.
Keyphrases
  • randomized controlled trial
  • systematic review
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