A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides.

Darja BeyerChristian VaccarinXavier DeupiAna Katrina MapanaoSusan CohrsFan Sozzi-GuoPascal V GrundlerNicholas P van der MeulenJinling WangMatthias TanriverJeffrey W BodeRoger SchibliCristina Müller

Published in: EJNMMI research (2023)

Ga-labeling at high molar activity, which would be essential to obtain images with high signal-to-background contrast to detect (patho)physiological ACE2 expression levels in patients.

Keyphrases

sars cov
angiotensin converting enzyme
angiotensin ii
poor prognosis
pet ct
high resolution
magnetic resonance
deep learning
respiratory syndrome coronavirus
optical coherence tomography
computed tomography
convolutional neural network
cell therapy
mesenchymal stem cells
bone marrow
coronavirus disease