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Cyto-Histological Profile of MicroRNAs as Diagnostic Biomarkers in Differentiated Thyroid Carcinomas.

Maria de Lurdes MatosMafalda PintoMarta AlvesSule CanberkAna GonçalvesMaria João BugalhoAna Luisa PapoilaPaula Soares
Published in: Genes (2024)
mutation, suggesting an interplay of these mutations with miRNAs expression. Despite this study having a relatively small sample size, overexpression of miRNAs in cytology may contribute to a more precise preoperative diagnosis. The miRNAs presented a good discriminative ability in PTC diagnosis. The association between the miRNAs expression profile and genetic alterations can be advantageous for an accurate diagnosis of DTCs/PTCs in FNAC.
Keyphrases
  • high grade
  • poor prognosis
  • cell proliferation
  • transcription factor
  • gene expression
  • genome wide
  • mass spectrometry
  • fine needle aspiration