Carvacrol reduces adipogenic differentiation by modulating autophagy and ChREBP expression.

Sonia SpallettaVincenzo FlatiElena ToniatoJacopo Di GregorioAntonio MarinoLaura PierdomenicoMarco MarchisioGabriella D'OraziIvana CacciatoreIole Robuffo

Published in: PloS one (2018)

The results support the notion that carvacrol, through its effect on autophagy (essential for adipocyte maturation) and on ChREBP activity, could be used as a valuable adjuvant to reduce adipogenic differentiation.

Keyphrases

signaling pathway
cell death
endoplasmic reticulum stress
poor prognosis
oxidative stress
adipose tissue
early stage
insulin resistance
type diabetes
skeletal muscle
long non coding rna