A Trial of Sertraline or Cognitive Behavior Therapy for Depression in Epilepsy.
Frank G GilliamKevin J BlackJewell CarterKenneth E FreedlandYvette I ShelineWei-Yann TsaiPatrick J LustmanPublished in: Annals of neurology (2019)
Depression remitted in just over one-half of subjects following sertraline or CBT. Despite the complex psychosocial disability associated with epilepsy, improving depression benefits quality of life. Serotonin reuptake inhibition does not appear to increase seizures or suicidality in persons with epilepsy. ANN NEUROL 2019;86:552-560.