Delivery of miR-214 via extracellular vesicles downregulates Xbp1 expression and pro-inflammatory cytokine genes in macrophages.
Gonzalo AlmanzaStephen SearlesMaurizio Zanetti
Published in: Extracellular vesicles and circulating nucleic acids (2024)
mRNA and downstream genes in macrophages. We propose miRNA-laden iEVs are a new approach to target macrophages and control immune dysregulation in the TME.