Effectiveness of strategies to suppress antibodies to infliximab in pediatric inflammatory bowel disease.

Jasmijn Z JagtKoen W HollemanMarc A BenningaJohan E Van LimbergenNanne K H de BoerTim G J de Meij

Published in: Journal of pediatric gastroenterology and nutrition (2023)

Dose optimization and/or adding an immunomodulator seem effective in suppressing low ATI titers. This strategy could also be considered in high ATI titers before switching.

Keyphrases

ulcerative colitis
randomized controlled trial
systematic review
signaling pathway