G protein-coupled receptor 158 modulates sensitivity to the sedative-hypnotic effect of ethanol in male mice.
Shoupeng WeiLei ZhengJinlong ChangJian JiangZhiyu ZhouHuanquan LiaoKun SongXiaoma LiuXinjin ChiHuiliang LiXin KuangNingning LiPublished in: Alcoholism, clinical and experimental research (2023)
This study reveals a critical role of neuronal GPR158 in shaping sensitivity to the sedative-hypnotic effect of ethanol, suggesting that GPR158 may be a potential target for treating alcohol use disorder.