Persistent GDNF Expression 45 Months after Putaminal Infusion of AAV2-GDNF in a Patient with Parkinson's Disease.

John D HeissAbhik Ray-ChaudhuryDavid E KleinerDebra J EhrlichGretchen ScottNancy A EdwardsDavid S GoldsteinDima A HammoudPiotr HadaczekVictor S Van LaarShantelle A GraffPeter HerscovitchCodrin LunguMark HallettRussell R LonserKareem A ZaghloulKrystof S Bankiewicz

Published in: Movement disorders : official journal of the Movement Disorder Society (2024)

F-FDOPA-PET signal, suggesting the regenerative potential of AAV2-GDNF in PD.

Keyphrases

gene therapy
stem cells
poor prognosis
mesenchymal stem cells
case report
low dose
computed tomography
cell therapy
positron emission tomography
pet imaging
tissue engineering
human health
risk assessment