PPAR Gamma and Angiogenesis: Endothelial Cells Perspective.

Published in: Journal of diabetes research (2016)

We summarize the current knowledge concerning PPARγ function in angiogenesis. We discuss the mechanisms of action for PPARγ and its role in vasculature development and homeostasis, focusing on endothelial cells, endothelial progenitor cells, and bone marrow-derived proangiogenic cells.

Keyphrases

endothelial cells
high glucose
insulin resistance
vascular endothelial growth factor
induced apoptosis
healthcare
cell cycle arrest
fatty acid
adipose tissue
type diabetes
oxidative stress
signaling pathway
cell proliferation
pi k akt