MRTF-A/SRF signaling suppresses invasion of oral squamous cell carcinoma.

Dan Yang Dan YangYuqing HeJiaxin LiuYansong Song Yu Zhou Lu Jiang Xin ZengXiaoping XuHao XuJing LiHongxia Dan

Published in: Oral diseases (2023)

SRF was closely related to the prognosis of OSCC. High expression of SRF and its co-activator MRTF-A inhibited proliferation, migration, and invasion of OSCC cells in vitro, possibly via EMT suppression.

Keyphrases

signaling pathway
induced apoptosis
poor prognosis
epithelial mesenchymal transition
cell cycle arrest
oxidative stress
nuclear factor
cell death
cell migration
endoplasmic reticulum stress
binding protein
immune response
long non coding rna
toll like receptor