Amlodipine: Can act as an antioxidant in patients with transfusion-dependent β-thalassemia? A double-blind, controlled, crossover trial.

Hadi Darvishi-KhezriHadiseh Khalilzadeh ArjmandiAily AliasgharianFatemeh ShakiMohammad ZahediMehrnoush KosaryanHossein KaramiRaheleh Naeimayi AaliEbrahim Salehifar

Published in: Journal of clinical laboratory analysis (2022)

Clinically, amlodipine therapy is an efficacious adjuvant treatment with conventional iron chelators for improving the levels of MDA and TAC in patients with TDT.

Keyphrases

hypertensive patients
sickle cell disease
early stage
clinical trial
cardiac surgery
oxidative stress
open label
phase iii
phase ii
blood pressure
anti inflammatory
stem cells
randomized controlled trial
mesenchymal stem cells
combination therapy
acute kidney injury
cell death
cell cycle arrest