Comparison of intraoperative fentanyl with dexmedetomidine for perioperative analgesia and opioid consumption during craniotomies: A randomised controlled pilot study with non-inferiority design.

Kamath SriganeshSeham SyedaHarsha ShanthannaSudhir VenkataramaiahSangeetha R Palaniswamy

Published in: International journal of clinical practice (2019)

A large-scale randomised controlled trial of perioperative dexmedetomidine versus fentanyl is feasible. Dexmedetomidine has the potential to be non-inferior to fentanyl for perioperative analgesia during craniotomies.

Keyphrases

cardiac surgery
pain management
patients undergoing
acute kidney injury
study protocol
ultrasound guided
chronic pain
postoperative pain
randomized controlled trial