The Role of ROCK in Platelet-Monocyte Collaborative Induction of Thromboinflammation during Acute Coronary Syndrome.

Ling-Wei HsuPo-Wei ChenWei-Ting ChangWen-Huang LeePing-Yen Liu

Published in: Thrombosis and haemostasis (2020)

Through ROCK-activated cytoskeleton remodeling and P-selectin expression, platelets were recruited and interacted synergistically with high CCR2-expressing monocytes to induce thromboinflammation in atherothrombosis.

Keyphrases

dendritic cells
acute coronary syndrome
poor prognosis
peripheral blood
regulatory t cells
percutaneous coronary intervention
antiplatelet therapy
quality improvement
immune response
endothelial cells
binding protein
long non coding rna
coronary artery disease
red blood cell