Prognostic role of high cathepsin D expression in breast cancer: a systematic review and meta-analysis.

Junho KangYeuni YuSeongdo JeongHansong LeeHye Jin HeoJeong Jun ParkHee Sam NaDai Sik KoYun Hak Kim

Published in: Therapeutic advances in medical oncology (2020)

Our meta-analysis suggests that high expression levels of cathepsin D are associated with a poor prognosis in breast cancer. Based on our subgroup analysis, we believe that cathepsin D can act as a marker for poor breast cancer prognosis and also as a therapeutic target for breast cancer.

Keyphrases

poor prognosis
long non coding rna
systematic review
clinical trial
binding protein
meta analyses
study protocol