Adjunctive Glucocorticoid Therapy in Patients with Septic Shock.
Balasubramanian VenkateshSimon FinferJeremy CohenDorrilyn RajbhandariYaseen ArabiRinaldo BellomoLaurent BillotMaryam CorreaParisa GlassMeg HarwardChristopher JoyceQiang LiColin McArthurAnders PernerAndrew RhodesKelly ThompsonSteve WebbJohn Myburghnull nullPublished in: The New England journal of medicine (2018)
Among patients with septic shock undergoing mechanical ventilation, a continuous infusion of hydrocortisone did not result in lower 90-day mortality than placebo. (Funded by the National Health and Medical Research Council of Australia and others; ADRENAL ClinicalTrials.gov number, NCT01448109 .).