Adaptive immune receptor features related to breast cancer tissue in Kenyan patients: high immunoglobulin gene expression and high levels of gamma-delta T-cells.
Kennedy W MwangiMoses K KamitaJacqueline W WaweruShahin SayedJonine D FigueroaStefan AmbsKonrad J CiosGeorge BlanckFrancis W MakokhaPublished in: Breast cancer research and treatment (2023)
For Kenyan patients, a high level of IG expression, representing specific CDR3 chemistries, was associated with BC. These results lay the foundation for studies that could support specific immunotherapeutic interventions for Kenyan BC patients.