Performance of non-invasive prenatal screening for fetal aneuploidy in twin pregnancies: a meta-analysis.

The meta-analysis results from 10 eligible studies demonstrated that NIPS has both high sensitivity and specificity for trisomy 21 screening in twin pregnancies. The results for trisomy 18 screening are less satisfactory than those for trisomy 21. The performance for trisomy 13 screening could not be determined as only three cases were identified. © 2017 John Wiley & Sons, Ltd.